Finkbeiner A E, Bissada N K
Urol Res. 1981;9(6):281-8. doi: 10.1007/BF00257777.
The effects of prostaglandins on the urinary bladder and urethra were determined using guinea pig detrusor and urethral muscle strips in an in vitro muscle bath. Prostaglandins E1, E2, F1a and F2a caused contraction of detrusor strips and relaxation of strips from the bladder outlet. Their mechanism of action appears to be mediated through the sympathetic nervous system in both the detrusor and outlet with some direct relaxation effects in the outlet.
在体外肌肉浴中，使用豚鼠逼尿肌和尿道肌条来确定前列腺素对膀胱和尿道的影响。前列腺素E1、E2、F1a和F2a可引起逼尿肌条收缩以及膀胱出口处肌条松弛。它们的作用机制似乎是通过逼尿肌和出口处的交感神经系统介导的，在出口处还有一些直接的松弛作用。
