Wells C L, Stern J R, Hecht L H
Eur J Appl Physiol Occup Physiol. 1982;48(1):41-9. doi: 10.1007/BF00421163.
The subjects of this experiment were well-trained men (6) and women (4) participating in a marathon race in Phoenix, Arizona, on a cool, cloudy, windy day. Venous blood was collected one week prior to the run, immediately after, and 4, 8, and 24 h after the race. There were no significant changes in hematocrit, hemoglobin, or red blood cell counts following the race. The sample collected immediately after the race showed a pronounced leucocytosis. Differential counts showed that this increase in white blood cell count was limited to polymorphonuclear cells, suggesting that an inflammatory response to stress of the race was involved. Percentage changes in blood volume, red blood cell volume, and plasma volume were calculated from hematocrit and hemoglobin changes. These changes showed that there was reduction of plasma volume of 8% for females and 13% for males immediately after the race, with return to initial values within 8 h. We suggest that the increase in protein following the race was contributed by the flow of lymph from muscle to the vascular compartment.
本实验的受试者为训练有素的男性（6名）和女性（4名），他们在凉爽、多云且有风的日子里参加了亚利桑那州凤凰城的一场马拉松比赛。在比赛前一周、比赛结束后即刻以及比赛后4小时、8小时和24小时采集静脉血。赛后血细胞比容、血红蛋白或红细胞计数无显著变化。比赛结束后即刻采集的样本显示出明显的白细胞增多。分类计数表明，白细胞计数的这种增加仅限于多形核细胞，这表明涉及对比赛应激的炎症反应。根据血细胞比容和血红蛋白的变化计算血容量、红细胞体积和血浆体积的百分比变化。这些变化表明，比赛后即刻女性血浆体积减少8%，男性减少13%，8小时内恢复到初始值。我们认为，赛后蛋白质的增加是由淋巴从肌肉流向血管腔所致。
