乳酸脱氢酶升高病毒并发感染加剧小鼠疟疾
Exacerbation of murine malaria by concurrent infection with lactic dehydrogenase-elevating virus.
作者信息
Henderson D C, Tosta C E, Wedderburn N
出版信息
Clin Exp Immunol. 1978 Aug;33(2):357-9.
Abstract
The simultaneous infection of mice with lactic dehydrogenase-elevating virus (LDV) and Plasmodium yoelii resulted in an exacerbated attack of malaria. Peak parasitaemia was higher and the patent infection more prolonged in doubly infected mice. The results indicate that contamination with LDV must be considered when a change in parasite virulence is observed, particularly when the parasite is maintained by blood passage in mice.
摘要
小鼠同时感染乳酸脱氢酶升高病毒（LDV）和约氏疟原虫会导致疟疾发作加剧。双重感染小鼠的寄生虫血症峰值更高，显性感染持续时间更长。结果表明，当观察到寄生虫毒力发生变化时，尤其是当寄生虫通过在小鼠体内传代血液来维持时，必须考虑LDV污染的情况。
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