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一种用于人体局部麻醉药比较的模型。

A model for comparison of local anesthetics in man.

作者信息

McQuay H, Weir L, Porter B, O'Sullivan G, Paterson G, Moore A, Bullingham R

出版信息

Anesth Analg. 1982 May;61(5):418-22.

PMID:7199865
Abstract

Ten patients scheduled for bilateral arm surgery were given general anesthesia plus, on one side, an axillary brachial plexus block. Ten additional patients scheduled for bilateral foot surgery were similarly given general anesthesia plus an ankle block on one side. A within-patient blind comparison of postoperative analgesia between blocked and unblocked side was performed. An additional 10 patients scheduled for bilateral foot surgery had one side blocked with lidocaine and the other side blocked with bupivacaine for comparison of postoperative analgesia. Postoperative analgesia recorded by a nurse observed was significantly better on the blocked side compared with the unblocked side. This difference was greater for ankle blocks. There were no differences between the analgesic measures for lidocaine and bupivacaine ankle blocks over the 6-hour study period.

摘要

十名计划进行双臂手术的患者接受了全身麻醉,并且在一侧进行了腋路臂丛神经阻滞。另外十名计划进行双脚手术的患者同样接受了全身麻醉,并在一侧进行了踝关节阻滞。对患者体内阻滞侧和未阻滞侧的术后镇痛效果进行了盲法比较。另有十名计划进行双脚手术的患者,一侧用利多卡因阻滞,另一侧用布比卡因阻滞,以比较术后镇痛效果。护士观察记录到,与未阻滞侧相比,阻滞侧的术后镇痛效果明显更好。踝关节阻滞的这种差异更大。在6小时的研究期间,利多卡因和布比卡因踝关节阻滞的镇痛措施之间没有差异。

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