海洛因“过量”死亡：与毒品相关的环境线索的作用
Heroin "overdose" death: contribution of drug-associated environmental cues.
作者信息
Siegel S, Hinson R E, Krank M D, McCully J
出版信息
Science. 1982 Apr 23;216(4544):436-7. doi: 10.1126/science.7200260.
PMID:7200260
Abstract
A model of "overdose" deaths among heroin addicts is proposed which emphasizes recent findings concerning the contribution of drug-associated environmental cues to drug tolerance. Results of animal experiments performed to evaluate this model suggest that conditioned drug-anticipatory responses, in addition to pharmacological factors, affect heroin-induced mortality.
摘要
本文提出了一种海洛因成瘾者“过量用药”死亡的模型，该模型强调了有关药物相关环境线索对药物耐受性影响的最新研究结果。为评估该模型而进行的动物实验结果表明，除了药理学因素外，条件性药物预期反应也会影响海洛因诱发的死亡率。
Zotero 插件