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输血传播巴贝斯虫病的成功化疗

Successful chemotherapy of transfusion babesiosis.

作者信息

Wittner M, Rowin K S, Tanowitz H B, Hobbs J F, Saltzman S, Wenz B, Hirsch R, Chisholm E, Healy G R

出版信息

Ann Intern Med. 1982 May;96(5):601-4. doi: 10.7326/0003-4819-96-5-601.

DOI:10.7326/0003-4819-96-5-601
PMID:7200341
Abstract

We describe babesiosis transmitted by transfusion. The infected blood donor was identified and a minimum period of infectivity of the donor's blood was established. We report a new modality for chemotherapy consisting of quinine plus clindamycin, and a new endemic focus for this zoonosis on Fire Island, New York. There are insufficient data to establish a reasonably safe period after which visitors and residents of Babesia-endemic foci can become blood donors. Screening of such persons by a rapid serologic test, such as the ELISA or immunofluorescent antibody tests, is suggested.

摘要

我们描述了通过输血传播的巴贝斯虫病。已识别出受感染的献血者,并确定了献血者血液的最短感染期。我们报告了一种由奎宁加克林霉素组成的化疗新方法,以及纽约火岛这种人畜共患病的一个新的地方病疫源地。目前尚无足够数据确定巴贝斯虫病疫源地的访客和居民在多长时间后可以安全献血。建议通过快速血清学检测,如酶联免疫吸附测定(ELISA)或免疫荧光抗体检测对此类人员进行筛查。

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1
Successful chemotherapy of transfusion babesiosis.输血传播巴贝斯虫病的成功化疗
Ann Intern Med. 1982 May;96(5):601-4. doi: 10.7326/0003-4819-96-5-601.
2
Transfusion-transmitted babesiosis in an immunocompromised patient: a case report and review.免疫功能低下患者的输血传播巴贝斯虫病:病例报告与复习。
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A cluster of transfusion-associated babesiosis cases traced to a single asymptomatic donor.一组与输血相关的巴贝斯虫病病例追溯到一名无症状献血者。
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Fulminant babesiosis treated with clindamycin, quinine, and whole-blood exchange transfusion.用克林霉素、奎宁和全血置换输血治疗的暴发性巴贝斯虫病。
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Transfusion-associated transmission of babesiosis in New York State.纽约州输血相关的巴贝斯虫病传播
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Transfusion-transmitted babesiosis: a case report from a new endemic area.输血传播的巴贝斯虫病:来自一个新的流行地区的病例报告。
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Vertically transmitted babesiosis.垂直传播的巴贝斯虫病。
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Transfusion-acquired babesiosis and failure of antibiotic treatment.
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引用本文的文献

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Case Report: Overwhelming Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone.病例报告:通过红细胞单采术以及克林霉素、阿奇霉素和阿托伐醌三联疗法迅速成功治疗严重寄生虫血症
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2
Experimental transfusion-induced Babesia microti infection: dynamics of parasitemia and immune responses in a rhesus macaque model.实验性输血诱导的微小巴贝斯虫感染:恒河猴模型中的寄生虫血症动态和免疫反应
Transfusion. 2016 Jun;56(6 Pt 2):1508-19. doi: 10.1111/trf.13521. Epub 2016 Feb 19.
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Babesiosis.
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Identification and characterization of the RouenBd1987 Babesia divergens Rhopty-Associated Protein 1.鲁昂Bd1987分歧巴贝斯虫罗普蒂相关蛋白1的鉴定与特性分析
PLoS One. 2014 Sep 16;9(9):e107727. doi: 10.1371/journal.pone.0107727. eCollection 2014.
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Epidemiology of infections in cancer patients.癌症患者感染的流行病学
Cancer Treat Res. 2014;161:43-89. doi: 10.1007/978-3-319-04220-6_2.
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A longitudinal study of Babesia microti infection in seropositive blood donors.对血清阳性献血者中微小巴贝斯虫感染的纵向研究。
Transfusion. 2014 Sep;54(9):2217-25. doi: 10.1111/trf.12622. Epub 2014 Mar 28.
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Infection. 2013 Dec;41(6):1057-72. doi: 10.1007/s15010-013-0526-8. Epub 2013 Oct 9.
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Babesia: an emerging infectious threat in transfusion medicine.巴贝斯虫:输血医学中一种新出现的感染威胁。
PLoS Pathog. 2013;9(7):e1003387. doi: 10.1371/journal.ppat.1003387. Epub 2013 Jul 11.
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Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti.从人类病原体微小巴贝斯虫中测序最小的顶复门基因组。
Nucleic Acids Res. 2012 Oct;40(18):9102-14. doi: 10.1093/nar/gks700. Epub 2012 Jul 24.
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Can J Infect Dis. 1998 Nov;9(6):387-9. doi: 10.1155/1998/564190.