Carlson J C, Buhr M M, Wentworth R, Hansel W
Endocrinology. 1982 May;110(5):1472-6. doi: 10.1210/endo-110-5-1472.
Microsomal membranes prepared from bovine corpora lutea (CL) were examined by wide angle x-ray diffraction to determine if there were structural changes in the cellular membranes during regression. In samples prepared from CL removed at midcycle, all of the membrane lipid was in the liquid crystalline phase at body temperature. However, examination of microsomes prepared from regressing luteal tissue revealed a phase transition in which a portion of the lipid bilayer was in a gel phase at body temperature. Coincident with this physical change was a decline in CL function. These results indicate that there are structural changes that occur at the submicroscopic level in cellular membranes during luteal regression, which appear to be related to the loss in cellular function.
通过广角X射线衍射对从牛黄体（CL）制备的微粒体膜进行了检查，以确定在黄体退化过程中细胞膜是否存在结构变化。在从中周期取出的CL制备的样品中，所有膜脂在体温下均处于液晶相。然而，对从退化的黄体组织制备的微粒体的检查显示出一种相变，其中一部分脂质双层在体温下处于凝胶相。与这种物理变化同时发生的是CL功能的下降。这些结果表明，在黄体退化过程中细胞膜在亚微观水平上发生了结构变化，这似乎与细胞功能的丧失有关。
