Nilsson C G, Luukkainen T, Lähteenmäki P
Contraception. 1978 Jun;17(6):569-73. doi: 10.1016/s0010-7824(78)80009-2.
Eight healthy women had a d-norgestrel-releasing intrauterine device inserted postmenstrually and maintained in the uterine cavity for a one year period. Plasma concentrations of d-norgestrel were measured by radioimmunoassay during the one year treatment period. d-Norgestrel could be detected in the plasma of all the subjects within a fairly narrow range during the whole period. The release rate of d-norgestrel was calculated from two IUDs removed after the treatment.
八名健康女性在月经后放置了含炔诺孕酮的宫内节育器，并在子宫腔内保留一年。在这一年的治疗期间，通过放射免疫分析法测定血浆中炔诺孕酮的浓度。在整个期间内，所有受试者的血浆中均可在相当窄的范围内检测到炔诺孕酮。根据治疗后取出的两个宫内节育器计算炔诺孕酮的释放率。
