Amon K, Amon I, Scharp H
Zentralbl Gynakol. 1982;104(2):137-41.
Pathogenic anaerobic bacteria may be among the causes of puerperal mastitis which, therefore, was treated by the authors with metronidazole (Vagimid) and with antibiotics, such as penicillin, oxacillin, erythromycin, and oxytetracycline. Best results were obtained by administration of metronidazole to patients in early mastitis. The frequency of incisions was reduced. The therapeutic results obtained from the use of metronidazole on patients with advanced mastitis were identical with those obtained from antibiotics.--Metronidazole concentrations were equal in serum and milk. No side effects were observed.
致病性厌氧菌可能是产褥期乳腺炎的病因之一,因此,作者用甲硝唑(灭滴灵)和抗生素如青霉素、苯唑西林、红霉素及土霉素对其进行治疗。对早期乳腺炎患者使用甲硝唑可取得最佳效果,切开引流的频次降低。对晚期乳腺炎患者使用甲硝唑的治疗效果与使用抗生素相同。血清和乳汁中的甲硝唑浓度相等,未观察到副作用。