Fosså S D, Odegaard A, Kaalhus O
Eur Urol. 1981;7(3):150-6. doi: 10.1159/000473206.
The 5- and 10-year survival rate was 25 and 16%, respectively, in 107 patients with P2 and P3 bladder carcinoma treated with partial cystectomy followed by postoperative high voltage irradiation. The depth of tumour infiltration was of major prognostic significance though patients with P3a tumours had a significantly better prognosis than those with P2 carcinomas. Within the same P category, the histological differentiation represented no prognostic factor. Patients with tumours without blood vessel and/or lymphatic vessel infiltration survived significantly longer than patients with such infiltration. High voltage postoperative irradiation prolonged survival in some patient groups (non-radically operated tumours, early tumour recurrence, grade III tumours) only if irradiation was supplied with high cumulative radiation effect (CRE) values.
107例接受部分膀胱切除术并术后进行高电压照射的P2和P3期膀胱癌患者，其5年和10年生存率分别为25%和16%。肿瘤浸润深度具有重要的预后意义，尽管P3a期肿瘤患者的预后明显好于P2期癌患者。在同一P分期内，组织学分化不是预后因素。肿瘤无血管和/或淋巴管浸润的患者生存时间明显长于有此类浸润的患者。术后高电压照射仅在给予高累积辐射效应（CRE）值时，才会延长某些患者组（非根治性手术肿瘤、早期肿瘤复发、III级肿瘤）的生存期。
