Zonta F, D'Agostino G, Grana E
Farmaco Sci. 1980 Dec;35(12):1005-14.
The mechanical response of the rat vas deferens observed following administration of single or cumulative doses of K+ was studied and then the influence of external Ca2+ on the K+ response was investigated. The response of the preparation to noradrenalin when the concentration of K+ and/or Ca2+ is different from the physiological one was also studied. The results indicate that the ability of K+ to increase free intracellular Ca2+ concentration is greater than that of noradrenalin; there is an increase in the maximal response to noradrenalin on increasing the external concentration of K+ and/or Ca2+.
研究了单次或累积给予钾离子（K⁺）后大鼠输精管的机械反应，随后研究了细胞外钙离子（Ca²⁺）对K⁺反应的影响。还研究了在K⁺和/或Ca²⁺浓度不同于生理浓度时，该制剂对去甲肾上腺素的反应。结果表明，K⁺增加细胞内游离Ca²⁺浓度的能力大于去甲肾上腺素；增加细胞外K⁺和/或Ca²⁺浓度时，对去甲肾上腺素的最大反应增强。
