Nishida K, Yoshikawa T, Kondo M, Thiele H G
Hepatogastroenterology. 1980 Dec;27(6):488-94.
Carcinoembryonic antigen (CEA) levels in the pure pancreatic juice collected endoscopically were measured in a total of 102 cases including 18 with pancreatic cancer using radioimmunoassay. CEA levels in the pancreatic juice were significantly higher (p less than 0.001) in patients with pancreatic cancer than in those with pancreatitis or with other miscellaneous diseases and in normal controls. Despite the elevated CEA level in the pancreatic juice from patients with pancreatic cancer without liver metastasis, their serum CEA did not necessarily reveal a high value. In contrast, CEA in the pancreatic juice from patients with an advanced stage with liver metastasis, did not show a high value, although some of them had high CEA in their sera. It is concluded that the estimation of CEA levels in the pancreatic juice provides important diagnostic information in the detection of pancreatic cancer in the early stage.
采用放射免疫分析法对102例患者经内镜采集的纯胰液中的癌胚抗原（CEA）水平进行了检测，其中包括18例胰腺癌患者。胰腺癌患者胰液中的CEA水平显著高于胰腺炎、其他杂病患者及正常对照（p＜0.001）。胰腺癌无肝转移患者胰液中CEA水平升高，但血清CEA不一定升高。相反，晚期有肝转移患者的胰液CEA水平不高，尽管部分患者血清CEA水平升高。结论：胰液CEA水平检测对早期胰腺癌的诊断具有重要意义。
