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Hydroxyethyl starch-induced macroamylasemia.

作者信息

Köhler H, Kirch W, Horstmann H J

出版信息

Int J Clin Pharmacol Biopharm. 1977 Sep;15(9):428-31.

PMID:72048
Abstract

Summarizing, the following results were obtained: 1. After infusion of 500 ml hydroxyethyl starch 6% in all patients an increase of serum amylase occurred, which in most cases reached values twice as high as the basal value. 2. This hyperamylasemia is caused by the formation of a high molecular HES-amylase complex, which cannot be easily eliminated. 3. In no case was hyperamylasemia associated with other clinical signs or symptoms.

摘要

相似文献

1
Hydroxyethyl starch-induced macroamylasemia.
Int J Clin Pharmacol Biopharm. 1977 Sep;15(9):428-31.
2
[Hyperamylasemia following infusion of hydroxyethyl starch with different molecular weight distributions].
Infusionsther Klin Ernahr. 1977 Jun;4(3):141-4.
3
Studies on hydroxyethyl starch. Part II: Changes of the molecular weight distribution for hydroxyethyl starch types 450/0.7, 450/0.5, 450/0.3, 300/0.4, 200/0.7, 200/0.5, 200/0.3 and 200/0.1 after infusion in serum and urine of volunteers.羟乙基淀粉的研究。第二部分:450/0.7、450/0.5、450/0.3、300/0.4、200/0.7、200/0.5、200/0.3和200/0.1型羟乙基淀粉在志愿者血清和尿液中输注后的分子量分布变化
Arzneimittelforschung. 1985;35(3):615-22.
4
[Blood volume replacement and hemodilution with hydroxyethyl starch].[羟乙基淀粉用于血容量补充和血液稀释]
Infusionsther Klin Ernahr. 1978 Jun;5(3):169-77.
5
Macroamylasemia induced by hydroxyethyl starch--confirmation by gel filtration analysis of serum and urine.
Am J Clin Pathol. 1980 Oct;74(4):387-91. doi: 10.1093/ajcp/74.4.387.
6
Macroamylasaemia after treatment with hydroxyethyl starch.
Eur J Clin Invest. 1977 Jun;7(3):205-11. doi: 10.1111/j.1365-2362.1977.tb01599.x.
7
Macroamylasaemia following the infusion of low molecular weight-hydroxyethyl starch in man.
Eur Surg Res. 1979;11(4):217-22. doi: 10.1159/000128069.
8
[Clinical experiences with a 6% hydroxyethyl starch 40000 solution; metabolic parameters and tolerance].
Infusionsther Klin Ernahr. 1978 Apr;5(2):93-8.
9
[Second increase in plasma volume after single infusion of hydroxyethyl starch (author's transl)].单次输注羟乙基淀粉后血浆容量的第二次增加(作者译)
Klin Wochenschr. 1978 Oct 1;56(19):977-83. doi: 10.1007/BF01480153.
10
[Second effect on volume after a one-time infusion of hydroxyethyl starch].
Verh Dtsch Ges Inn Med. 1977;83:1756-8.

引用本文的文献

1
Pharmacokinetics and safety of 6 % hydroxyethyl starch 130/0.4 in healthy male volunteers of Japanese ethnicity after single infusion of 500 ml solution.日本裔健康男性志愿者单次输注 500ml 溶液后 6%羟乙基淀粉 130/0.4 的药代动力学和安全性。
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2
Macroamylasemia and other immunoglobulin-complexed enzyme disorders.巨淀粉酶血症及其他免疫球蛋白复合酶紊乱症。
West J Med. 1980 Nov;133(5):392-407.
3
Adverse reactions to plasma volume expanders.血浆容量扩充剂的不良反应。
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Use of plasma volume expanders in myocardial revascularisation.血浆容量扩充剂在心肌血运重建中的应用。
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