印度马兜铃中马兜铃酸甲酯对雌性小鼠生育力的影响。
Effect of methyl ester of aristolic acid from Aristolochia indica Linn. on fertility of female mice.
作者信息
Pakrashi A, Shaha C
出版信息
Experientia. 1978 Sep 15;34(9):1192-3. doi: 10.1007/BF01922952.
PMID:720520
Abstract
Methyl ester of aristolic acid, a pure compound isolated from the roots of Aristolochia indica (Linn.), was found to exert 100% abortifacient activity at a single oral dose of 60 mg/kg b. wt when administered on 6th or 7th day of pregnancy; 20 and 25% abortifacient effect were observed at the same dose on day 10 and 12, respectively.
摘要
从印度马兜铃（马兜铃属）根中分离出的纯化合物马兜铃酸甲酯，在妊娠第6天或第7天以60毫克/千克体重的单次口服剂量给药时，显示出100%的堕胎活性；在第10天和第12天以相同剂量给药时，分别观察到20%和25%的堕胎效果。
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