Kabidul Azam Md Nur, Rahman Md Mizanur, Biswas Samanta, Ahmed Md Nasir
Ethnobotany & Ethnomedicine Division, TechB Herbal Solution, Kushtia 7040, Bangladesh.
Medical College for Women & Hospital (MCW&H), Uttara Model Town, Dhaka 1230, Bangladesh.
Int Sch Res Notices. 2016 Jan 14;2016:7832120. doi: 10.1155/2016/7832120. eCollection 2016.
Cancer is a group of diseases which is categorized to differentiate into diverse cell types and move around in the body to sites of organogenesis that is key to the process of tumor genesis. All types of cancer fall into the group of malignant neoplastic diseases. In Bangladesh, cancer is now one of the foremost killer diseases and its personal, social, and economic bearing are huge. Plant-derived natural compounds (vincristine, vinblastine, etoposide, paclitaxel, camptothecin, topotecan, and irinotecan) are useful for the treatment of cancer. Since there is no extensive ethnobotanical research study in Bangladesh regarding the traditional uses of medicinal plants against neoplasms, therefore, a randomized ethnopharmacological surveys were carried out in 3 districts of Bangladesh to learn more about the usage of anticancer medicinal plants and their chemical constituents having antineoplastic activity. Comprehensive interviews were conducted to the folk medicine practitioners and medicinal plants as pointed out by them were photographed, collected, deposited, and identified at the Bangladesh National Herbarium. The various plant parts have been used by the healers which included whole plant, leaves, fruits, barks, roots, and seeds. This study evaluated considerable potential for discovery of novel compounds with less side effects in the management and prevention of malignancy in cancer.
癌症是一类疾病,其特征是能够分化为不同的细胞类型,并在体内转移至器官发生部位,而这一过程是肿瘤发生的关键。所有类型的癌症都属于恶性肿瘤疾病范畴。在孟加拉国,癌症现已成为主要的致命疾病之一,其对个人、社会和经济造成的影响巨大。植物源天然化合物(长春新碱、长春花碱、依托泊苷、紫杉醇、喜树碱、拓扑替康和伊立替康)对癌症治疗有益。由于在孟加拉国,尚未针对药用植物治疗肿瘤的传统用途开展广泛的民族植物学研究,因此,在孟加拉国的3个地区进行了随机的民族药理学调查,以进一步了解具有抗肿瘤活性的抗癌药用植物及其化学成分的使用情况。对民间医学从业者进行了全面访谈,并对他们指出的药用植物进行拍照、收集、存放,然后在孟加拉国国家植物标本馆进行鉴定。治疗者使用了各种植物部位,包括整株植物、叶子、果实、树皮、根和种子。这项研究评估了在癌症恶性肿瘤的管理和预防中发现副作用较小的新型化合物的巨大潜力。