• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

性反转胎儿小鼠睾丸中生殖细胞的命运。

The fate of germ cells in the testis of fetal Sex-reversed mice.

作者信息

McLaren A

出版信息

J Reprod Fertil. 1981 Mar;61(2):461-7. doi: 10.1530/jrf.0.0610461.

DOI:10.1530/jrf.0.0610461
PMID:7205792
Abstract

XX germ cells in the fetal testes of XX Sex-reverse male mice were observed mostly to develop in the same manner as do XY germ cells in a normal fetal testis; but some, in the vicinity of the mesonephric rete region, entered the prophase of meiosis at the same time as do XX germ cells in a normal fetal ovary. No germ cells in meiosis were found in the fetal testes of XY males, nor of XO Sex-reversed males. It is suggested that a second X chromosome renders a germ cell more susceptible to the meiosis-inducing influence of the mesonephric rete.

摘要

在XX性反转雄性小鼠的胎儿睾丸中,XX生殖细胞大多以与正常胎儿睾丸中的XY生殖细胞相同的方式发育;但一些位于中肾网区域附近的生殖细胞,与正常胎儿卵巢中的XX生殖细胞同时进入减数分裂前期。在XY雄性以及XO性反转雄性的胎儿睾丸中均未发现处于减数分裂期的生殖细胞。这表明第二条X染色体使生殖细胞更容易受到中肾网诱导减数分裂的影响。

相似文献

1
The fate of germ cells in the testis of fetal Sex-reversed mice.性反转胎儿小鼠睾丸中生殖细胞的命运。
J Reprod Fertil. 1981 Mar;61(2):461-7. doi: 10.1530/jrf.0.0610461.
2
X-chromosome activity in the germ cells of sex-reversed mouse embryos.性反转小鼠胚胎生殖细胞中的X染色体活性
J Reprod Fertil. 1981 Nov;63(2):533-7. doi: 10.1530/jrf.0.0630533.
3
Meiotic germ cells antagonize mesonephric cell migration and testis cord formation in mouse gonads.减数分裂的生殖细胞拮抗小鼠性腺中中肾细胞的迁移和睾丸索的形成。
Development. 2003 Dec;130(24):5895-902. doi: 10.1242/dev.00836. Epub 2003 Oct 15.
4
Onset and progress of meiotic prophase in the oocytes in the B6.YTIR sex-reversed mouse ovary.B6.YTIR性反转小鼠卵巢中卵母细胞减数分裂前期的起始与进程
Biol Reprod. 2003 Dec;69(6):1879-89. doi: 10.1095/biolreprod.103.017541. Epub 2003 Aug 6.
5
Induction of meiosis in fetal mouse testis in vitro.体外诱导胎鼠睾丸减数分裂
Dev Biol. 1976 Sep;52(2):193-200. doi: 10.1016/0012-1606(76)90239-6.
6
Sex determination in mammalian germ cells: extrinsic versus intrinsic factors.哺乳动物生殖细胞性别决定:外在因素与内在因素。
Reproduction. 2010 Jun;139(6):943-58. doi: 10.1530/REP-10-0075. Epub 2010 Apr 15.
7
Accelerated germ cell apoptosis in sex chromosome aneuploid fetal human gonads.性染色体非整倍体胎儿人类性腺中生殖细胞凋亡加速。
Mol Hum Reprod. 2003 Apr;9(4):219-25. doi: 10.1093/molehr/gag031.
8
The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary.在B6.Y(TIR)性反转小鼠卵巢减数分裂前期,卵母细胞中X和Y染色体的行为。
Reproduction. 2008 Feb;135(2):241-52. doi: 10.1530/REP-07-0383.
9
Studies on mouse germ cells inside and outside the gonad.关于性腺内外小鼠生殖细胞的研究。
J Exp Zool. 1983 Nov;228(2):167-71. doi: 10.1002/jez.1402280203.
10
A study of meiosis in chimeric mouse fetal gonads.嵌合小鼠胎儿性腺减数分裂的研究。
Development. 1990 May;109(1):37-40. doi: 10.1242/dev.109.1.37.

引用本文的文献

1
Gonadal sex and temperature independently influence germ cell differentiation and meiotic progression in .性腺性别和温度独立影响生殖细胞的分化和减数分裂进程。
Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2413191121. doi: 10.1073/pnas.2413191121. Epub 2024 Dec 30.
2
Sex determination without sex chromosomes.无性染色体的性别决定。
Philos Trans R Soc Lond B Biol Sci. 2021 Aug 30;376(1832):20200109. doi: 10.1098/rstb.2020.0109. Epub 2021 Jul 12.
3
Aldehyde dehydrogenase 1A1: friend or foe to female metabolism?乙醛脱氢酶 1A1:女性代谢的朋友还是敌人?
Nutrients. 2014 Mar 3;6(3):950-73. doi: 10.3390/nu6030950.
4
Aberrant gene expression and sexually incompatible genomic imprinting in oocytes derived from XY mouse embryonic stem cells in vitro.体外培养的 XY 小鼠胚胎干细胞来源的卵母细胞中异常的基因表达和性不兼容的基因组印记。
PLoS One. 2013;8(3):e58555. doi: 10.1371/journal.pone.0058555. Epub 2013 Mar 5.
5
Oocyte-like cells induced from mouse spermatogonial stem cells.由小鼠精原干细胞诱导产生的卵母细胞样细胞。
Cell Biosci. 2012 Aug 6;2(1):27. doi: 10.1186/2045-3701-2-27.
6
DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary.DMRT1 通过转录激活哺乳动物胎儿卵巢中的 Stra8 来促进卵子发生。
Dev Biol. 2011 Aug 1;356(1):63-70. doi: 10.1016/j.ydbio.2011.05.658. Epub 2011 May 20.
7
Germ cell sex determination: a collaboration between soma and germline.生殖细胞性别决定:体细胞与生殖系的协作。
Curr Opin Cell Biol. 2010 Dec;22(6):722-9. doi: 10.1016/j.ceb.2010.09.006. Epub 2010 Oct 26.
8
Instructing an embryonic stem cell-derived oocyte fate: lessons from endogenous oogenesis.指导胚胎干细胞来源的卵母细胞命运:来自内源性卵子发生的经验教训。
Endocr Rev. 2009 May;30(3):264-83. doi: 10.1210/er.2008-0034. Epub 2009 Apr 14.
9
X chromosome activity in mouse XX primordial germ cells.小鼠XX原始生殖细胞中的X染色体活性
PLoS Genet. 2008 Feb;4(2):e30. doi: 10.1371/journal.pgen.0040030.
10
Somatic control of germline sexual development is mediated by the JAK/STAT pathway.生殖系性发育的体细胞控制由JAK/STAT信号通路介导。
Nature. 2005 Jul 28;436(7050):563-7. doi: 10.1038/nature03849.