Moore R, Mills I H, Forster A
J R Soc Med. 1981 Feb;74(2):129-31. doi: 10.1177/014107688107400208.
The effects of a constant intravenous infusion of naloxone in doses ranging from 3.2 to 6.4 mg/day were studied in a group of patients with anorexia nervosa. Patients showed a significantly greater weight gain during the infusion compared with the periods before and after naloxone. Plasma β-hydroxybutyrate and non-esterified fatty acid levels fell during the infusion. It is suggested that, in man, naloxone has an antilipolytic effect in vivo.
对一组神经性厌食症患者研究了每日静脉输注3.2至6.4毫克剂量纳洛酮的效果。与输注纳洛酮之前和之后的时期相比，患者在输注期间体重显著增加。输注期间血浆β-羟基丁酸酯和非酯化脂肪酸水平下降。提示在人体内，纳洛酮在体内具有抗脂解作用。
