Sadovsky E, Yarkoni S
Fertil Steril. 1978 Nov;30(5):519-21. doi: 10.1016/s0015-0282(16)43631-9.
The multiload contraceptive intrauterine device (IUD) (ML Cu-250) is made of polyethylene and contains copper wire which is wrapped around the stem, providing 250 sq mm of exposed copper surface area. The IUD was inserted in 294 women comprising 1884 women-months of use. Four pregnancies and three expulsions occurred. In 13 instances the ML Cu-250 IUD was removed for medical reasons (side effects). The net cumulative pregnancy rate for a 12-month period after insertion was 3.9% and the expulsion rate was 1.6%; the medical removal rate was 8.2%. No perforations or tubal pregnancies occurred. Our results with the ML Cu-250 was compared with our previous experience with other IUDs. It seems that the comparatively low pregnancy, expulsion, and medical removal rates render the ML Cu-250 a good device for clinical use.
多负荷避孕宫内节育器(IUD)(ML Cu - 250)由聚乙烯制成,含有缠绕在杆上的铜线,提供250平方毫米的暴露铜表面积。该宫内节育器被插入294名女性体内,累计使用时间为1884个妇女 - 月。发生了4次妊娠和3次脱落。有13例因医学原因(副作用)取出ML Cu - 250宫内节育器。插入后12个月期间的净累积妊娠率为3.9%,脱落率为1.6%;医学取出率为8.2%。未发生穿孔或输卵管妊娠。我们将ML Cu - 250的结果与我们之前使用其他宫内节育器的经验进行了比较。看来相对较低的妊娠、脱落和医学取出率使ML Cu - 250成为一种临床使用的良好器械。