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一例注射潘库溴铵自杀事件:死后血液、血清及尿液中潘库溴铵荧光测定法的评估

A suicide by pancuronium bromide injection: evaluation of the fluorometric determination of pancuronium in postmortem blood, serum and urine.

作者信息

Poklis A, Melanson E G

出版信息

J Anal Toxicol. 1980 Nov-Dec;4(6):275-80. doi: 10.1093/jat/4.6.275.

Abstract

A fatal case of suicidal injection of pancuronium bromide is presented. Pancuronium was detected in blood and urine by ion-pair extraction and fluorometry. An evaluation of the fluorometric procedure for the determination of pancuronium in postmortem blood, serum and urine is presented. Stability of the extracted ion-pair, possible interferences from other drugs, and the effects of specimen storage were studied.

摘要

本文报告一例因自杀注射潘库溴铵致死的病例。采用离子对萃取和荧光法在血液和尿液中检测到了潘库溴铵。本文还对荧光法测定死后血液、血清和尿液中潘库溴铵的方法进行了评估。研究了萃取离子对的稳定性、其他药物可能产生的干扰以及样本储存的影响。

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