Kendall B, Holland I
Neuroradiology. 1981 Mar;21(2):93-6. doi: 10.1007/BF00342987.
A review was performed of the computed tomograms (CTs) of 500 children which had been reported as showing widening of the supratentorial subarachnoid spaces with normal cerebral substance. On the basis of this a radiological diagnosis of cerebral atrophy had been made in all but five, who were said to have megalencephaly. From these, the children with large or abnormally enlarging heads, but normal or only slightly enlarged ventricles, were selected; there were 40 such cases (8%). The clinical condition either improved or remained stable over a period of 2 years; in the majority the scan abnormality regressed (22.5%) or remained static (67.5%). In three cases there was slight progression of the CT changes before stabilisation, but only one case developed classical communicating hydrocephalus necessitating a shunt procedure. This condition is a generally benign and mild form of communicating hydrocephalus, for which an aetiological factor was apparent in about two-thirds of the cases studied.
对500例儿童的计算机断层扫描(CT)进行了回顾性研究,这些CT报告显示幕上蛛网膜下腔增宽而脑实质正常。基于此,除了5例被诊断为巨脑症的儿童外,其余所有儿童均被作出脑萎缩的放射学诊断。从这些病例中,挑选出头大或头围异常增大但脑室正常或仅轻度增大的儿童;共有40例(8%)。在2年的时间里,这些儿童的临床状况要么改善要么保持稳定;大多数情况下,扫描异常消退(22.5%)或保持不变(67.5%)。有3例在稳定之前CT改变有轻微进展,但只有1例发展为典型的交通性脑积水而需要进行分流手术。这种情况是一种普遍良性且轻度的交通性脑积水,在约三分之二的研究病例中可发现明显的病因。