Growth hormone enhances basement membrane thickening in experimental diabetes. A preliminary report.
作者信息
Osterby R, Seyer-Hansen K, Gundersen H J, Lundbaek K
出版信息
Diabetologia. 1978 Dec;15(6):487-9. doi: 10.1007/BF02342875.
PMID:720783
Abstract
Injection of porcine growth hormone (200 microgram) or saline 5 days a week for 16 to 20 weeks in streptozotocin-diabetic rats showed that compared to saline growth hormone produced a 2 1/2-fold larger increase in glomerular capillary basement membrane thickness (2p = 0.027). The possible significance of this effect of an elevated level of growth hormone for diabetic microangiopathy is discussed.
摘要
Zotero 插件