Grassi R, Macchia M, Dazzi F
Minerva Med. 1981 Feb 18;72(4-5):233-6.
Glycosylated haemoglobin (Hb A1) was measured by ion-exchange column chromatography in 70 normal subjects, 40 diabetics and 83 patients with chronic renal failure, including 54 on chronic dialysis. The results, compared with glycemic balance and renal function, suggest that the coexisting occurrence of any kind of chronic renal failure can really interfere with the blood level of the fast haemoglobin fractions, disclosing new interesting perspectives of diagnostic and clinic employment.
采用离子交换柱色谱法对70名正常受试者、40名糖尿病患者和83名慢性肾衰竭患者(包括54名接受长期透析的患者)进行糖化血红蛋白(Hb A1)测定。将结果与血糖平衡和肾功能进行比较后发现,任何类型的慢性肾衰竭的并存确实会干扰快速血红蛋白组分的血液水平,这揭示了诊断和临床应用方面新的有趣前景。