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感染巴西日圆线虫(线虫纲)的蛋白质营养不良大鼠的食物摄入量和体重变化

Changes in the food intake and body weight of protein-malnourished rats infected with Nippostrongylus brasiliensis (Nematoda).

作者信息

Crompton D W, Walters D E, Arnold S

出版信息

Parasitology. 1981 Feb;82(1):23-38. doi: 10.1017/s0031182000041834.

DOI:10.1017/s0031182000041834
PMID:7208102
Abstract

The daily food intake and related changes in body weight were measured in young rats which were fed on synthetic diets containing 1% (3 experiments), 2% (4 experiments) and 20% (1 experiment) casein respectively. Some rats were infected with Nippostrongylus brasiliensis and allowed to feed ad libitum, some remained uninfected and were allowed to feed ad libitum, while others, which were matched by initial weight with rats from the infected group, remained uninfected and were given only the same amount of food as that consumed during the previous 24 h by their infected partners. No significant differences were detected between the rats before the start of the infection. Thereafter, the food intake of the infected undernourished rats was usually found to be significantly lower and the loss of body weight significantly greater than those of the uninfected rats. In infection periods of relatively long duration, the pair-fed uninfected rats did not lose as much weight as their infected partners even though their food intake (1% and 2% casein) was the same. Although the food intake, and consequently the weight, of infected rats fed on the diet containing 20% casein were significantly less than in their uninfected partners, no significant differences were observed between the weights of the infected and pair-fed rats fed on this diet.

摘要

分别用含1%(3个实验)、2%(4个实验)和20%(1个实验)酪蛋白的合成日粮喂养幼鼠,测定其每日食物摄入量及体重的相关变化。部分大鼠感染巴西日圆线虫并任其自由采食,部分大鼠未感染并任其自由采食,而其他与感染组大鼠初始体重匹配的未感染大鼠,未感染但仅给予与其感染同伴前24小时所消耗食物量相同的食物。在感染开始前,各大鼠组之间未检测到显著差异。此后,通常发现受感染的营养不良大鼠的食物摄入量显著低于未感染大鼠,体重损失也显著大于未感染大鼠。在感染持续时间相对较长的时期,即使成对喂养的未感染大鼠的食物摄入量(1%和2%酪蛋白)相同,其体重减轻程度也不如感染同伴。尽管以含20%酪蛋白日粮喂养的感染大鼠的食物摄入量以及因此导致的体重显著低于未感染同伴,但在以该日粮喂养的感染大鼠和成对喂养大鼠的体重之间未观察到显著差异。

相似文献

1
Changes in the food intake and body weight of protein-malnourished rats infected with Nippostrongylus brasiliensis (Nematoda).感染巴西日圆线虫(线虫纲)的蛋白质营养不良大鼠的食物摄入量和体重变化
Parasitology. 1981 Feb;82(1):23-38. doi: 10.1017/s0031182000041834.
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Protein losing enteropathy associated with Nippostrongylus brasiliensis infestation and its impact on albumin homoeostasis in rats fed two levels of dietary protein.与巴西日圆线虫感染相关的蛋白丢失性肠病及其对两种膳食蛋白水平喂养大鼠白蛋白稳态的影响。
Clin Sci (Lond). 1986 May;70(5):469-75. doi: 10.1042/cs0700469.

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