用于限制酶切图谱分析的最小二乘法
Least-squares method for restriction mapping.
作者信息
Schroeder J L, Blattner F R
出版信息
Gene. 1978 Oct;4(2):167-74. doi: 10.1016/0378-1119(78)90028-8.
PMID:720832
Abstract
A least-squares procedure has been developed to aid in deriving restriction-fragment maps once the order of cutsites has been determined. A computer program which carries out this method can be used to map either linear or circular molecules.
摘要
一旦确定了切割位点的顺序，就已经开发出一种最小二乘法程序来辅助推导限制性片段图谱。执行此方法的计算机程序可用于绘制线性或环状分子的图谱。
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