Progression of renal artery fibromuscular dysplasia in 42 patients as seen on angiography.

Forty-two hypertensive patients with fibromuscular dysplasia who had angiographic evidence of the development of new disease or of the progression of existing disease were studied. Renal arterial disease was classified as medial fibroplasia with aneurysms (12 patients), subadventitial fibroplasia (24 patients), or intimal fibroplasia (6 patients). Progression of the disease was shown in all 42 patients during the follow-up period (from 1 month to 11 years and 4 months). The results indicate that all forms of fibromuscular dysplasia are progressive and have variable rates of progression.