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[粘连过程中胃淋巴流出的特征]

[Characteristics of gastric lymph outflow in the presence of an adhesive process].

作者信息

Kazakova Z Kh

出版信息

Vopr Onkol. 1981;27(2):85-8.

PMID:7210601
Abstract

Under study were some regularities in the formation of gastric adhesions lymph vessels taking into account the pretumor background lesions and age. The study was undertaken on 103 complexes of abdominal organs from person died at the age of 50-94 and from 74 patients operated upon for cancer arising from ulcers and due to chronic gastritis. In cancers caused by ulcers gastric adhesions with adjacent organs were found to be well developed, these occurred prior to ulcer malignant transformation and had an extensive network of lymph vessels being the routes for proliferation of neoplastic cells beyond the boundaries of the organ under unfavourable conditions of their growth in gastric walls due to the presence of scarring tissue in the periphery of ulcer. In cancers arising due to chronic gastritis adhesions would develop at late stages of the disease as a compensatory mechanism in significantly impaired lymphodynamics by the lesion. These were of no practical importance for tumor metastasizing, since a submucous gastric layer, loose and rich in lymph vessels, contributed to prompt tumor invasion of the stomach walls. In aged and senile patients a considerable deformation and reduction of lymph vessels in adhesions and in the stomach walls do not contribute to rapid growth and proliferation of a neoplasm.

摘要

考虑到肿瘤前背景病变和年龄,对胃粘连淋巴管形成的一些规律进行了研究。该研究对103例50 - 94岁死亡者的腹部器官复合体以及74例因溃疡和慢性胃炎引发癌症而接受手术的患者进行。在由溃疡引起的癌症中,发现与相邻器官的胃粘连发育良好,这些粘连在溃疡恶变之前就已出现,并且有广泛的淋巴管网络,在溃疡周边存在瘢痕组织的情况下,由于肿瘤细胞在胃壁生长的不利条件,这些淋巴管成为肿瘤细胞超出器官边界增殖的途径。在由慢性胃炎引起的癌症中,粘连在疾病晚期作为病变导致显著淋巴动力学受损的一种代偿机制而形成。这些对肿瘤转移没有实际重要性,因为胃黏膜下层疏松且富含淋巴管,有助于肿瘤迅速侵犯胃壁。在老年患者中,粘连和胃壁中淋巴管的相当大变形和减少不利于肿瘤的快速生长和增殖。

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