Casslén B, Astedt B
Acta Obstet Gynecol Scand. 1981;60(1):59-62. doi: 10.3109/00016348109154111.
The influence of an IUD on the fibrinolytic activity of uterine fluid was measured by radial enzyme diffusion on fibrin plates. In samples obtained from 48 women using Cu-IUDs, the fibrinolytic activity in mid-cycle phase was higher than that in the proliferative or the luteal phase. It increased in the premenstrual phase. Individual values before and after insertion of a Cu-T were determined in the proliferative-mid-cycle phase and the luteal phase in a group of 11 women. In contrast to earlier reports on the endometrium, the fibrinolytic activity of uterine fluid was lower after, than before, insertion of an IUD. This may be due to a lower concentration of activators and/or to an increased concentration of inhibitors of plasminogen activation.
通过在纤维蛋白平板上进行径向酶扩散来测定宫内节育器（IUD）对子宫液纤维蛋白溶解活性的影响。在从48名使用铜宫内节育器的女性中获取的样本中，月经周期中期的纤维蛋白溶解活性高于增殖期或黄体期。在经前期其活性增加。在一组11名女性的增殖期-月经周期中期和黄体期测定了放置铜-T前后的个体值。与先前关于子宫内膜的报道相反，放置宫内节育器后子宫液的纤维蛋白溶解活性低于放置前。这可能是由于激活剂浓度较低和/或纤溶酶原激活抑制剂浓度增加所致。
