实验性鼓膜穿孔的修复

Repair of experimental tympanic membrane perforations.

作者信息

Stenfors L E, Carlsöö B, Salén B, Winblad B

出版信息

Acta Otolaryngol. 1980 Nov-Dec;90(5-6):332-41. doi: 10.3109/00016488009131734.

Abstract

In this investigation the healing pattern of experimental central and marginal pars tensa perforations in cats and rats was studied by using light and scanning electronmicroscopic techniques. The perforations were closed by hyperplastic squamous epithelium exhibiting a marked keratin production. This keratin formed a membranous structure which primarily appeared to close the perforation. No ingrowth of squamous epithelium into the middle ear cavity could be detected. Generally speaking, the perforations had closed within 9-11 days in rats and within 12-14 days in cats.

摘要

在本研究中，运用光学显微镜和扫描电子显微镜技术，对猫和大鼠实验性鼓膜紧张部中央及边缘穿孔的愈合模式进行了研究。穿孔由增生的鳞状上皮封闭，该上皮表现出显著的角质生成。这种角质形成了一种膜状结构，其主要作用似乎是封闭穿孔。未检测到鳞状上皮长入中耳腔。一般而言，大鼠的穿孔在9至11天内闭合，猫的穿孔在12至14天内闭合。