Beck B, Friis B, Heilmann C, Pedersen F K, Valerius N H
Acta Paediatr Scand. 1980 Nov;69(6):797-801. doi: 10.1111/j.1651-2227.1980.tb07156.x.
A boy with severe combined immunodeficiency was found to have coexistent hyperimmunoglobulinaemia E, eosinophilia and impaired neutrophil chemotaxis. Based on the literature, a deficient regulatory function of the T-cell system is proposed as the basic defect leading to the observed impairment of the cellular and humoral immunity and, probably through hyper-immunoglobulinaemia E, to defective neutrophil chemotaxis.
一名患有严重联合免疫缺陷的男孩被发现同时存在高免疫球蛋白E血症、嗜酸性粒细胞增多和中性粒细胞趋化功能受损。基于文献，有人提出T细胞系统的调节功能缺陷是导致所观察到的细胞免疫和体液免疫受损的基本缺陷，并且可能通过高免疫球蛋白E血症导致中性粒细胞趋化功能缺陷。
