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下肢血管重建术后发生致命性心肌梗死。273例患者术后随访6至11年。

Fatal myocardial infarction following lower extremity revascularization. Two hundred seventy-three patients followed six to eleven postoperative years.

作者信息

Hertzer N R

出版信息

Ann Surg. 1981 Apr;193(4):492-8.

Abstract

Routine preoperative coronary angiography has been recommended to all patients scheduled for elective lower extremity revascularization at the Cleveland Clinic since 1978. Patients found to have severe, correctable coronary artery disease (CAD) have been advised to undergo myocardial revascularization prior to surgical management of lower extremity ischemia in an attempt to reduce the incidence of fatal postoperative myocardial infarction. In order to provide an historic standard with which the results of this approach may eventually be compared, complete follow-up information has been obtained for 95% of 273 consecutive patients who underwent lower extremity revascularization between 1969 and 1973. Fatal myocardial infarction accounted for 52% of early postoperative deaths and occurred in 3.3% of the entire series. Among the patients who survived operation, the five-year mortality rate was 20% and the 11-year mortality rate was 40%. Complications of CAD caused 50% of the deaths that occurred within five years postoperatively and 55% of the deaths that have occurred within 11 years. The incidence of fatal myocardial infarction within five years after operation among patients who had preoperatively evidence of CAD was statistically significant (p less than 0.01).

摘要

自1978年起,克利夫兰诊所就建议所有计划接受择期下肢血管重建术的患者进行常规术前冠状动脉造影。对于被发现患有严重且可纠正的冠状动脉疾病(CAD)的患者,建议在对下肢缺血进行手术治疗之前先进行心肌血管重建,以试图降低致命性术后心肌梗死的发生率。为了提供一个可最终与这种方法的结果进行比较的历史标准,我们获取了1969年至1973年间连续接受下肢血管重建术的273例患者中95%的完整随访信息。致命性心肌梗死占术后早期死亡的52%,在整个系列中发生率为3.3%。在存活的手术患者中,五年死亡率为20%,十一年死亡率为40%。CAD并发症导致术后五年内发生的死亡病例中有50%,以及十一年内发生的死亡病例中有55%。术前有CAD证据的患者术后五年内发生致命性心肌梗死的发生率具有统计学意义(p小于0.01)。

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