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藏毛窦发生的癌。

Carcinoma arising in pilonidal sinuses.

作者信息

Pilipshen S J, Gray G, Goldsmith E, Dineen P

出版信息

Ann Surg. 1981 Apr;193(4):506-12.

Abstract

Pilonidal carcinoma is an infrequent complication of pilonidal disease. The surgeon's suspicion should be raised in cases of longstanding pilonidal inflammation. The disease occurs most frequently in men. The lesion is often a well-differentiated squamous carcinoma. Wide excisions at the initial procedure following a brief period of local wound care, is the optimum treatment and increases the chances for a five-year survival. Definitive closure of the defect is delayed and accomplished by rotational flaps or skin grafts. It palpable nodes are present in the inguinal region they should be biopsied even though this does not necessarily connote metastasis. When inguinal node metastasis is present, this is associated with a poor prognosis. The incidence of occult node metastasis is not known because no prophylactic groin dissections were performed. Staged groin dissections were not associated with any long-term survivals. The series was too small to determine its palliative potential. Radiation therapy may palliate local bone or soft tissue recurrences. Re-excisions of local soft tissue recurrences can provide, in some instances, long disease-free intervals. Both topical and systemic chemotherapy were administered in more recent cases with poor results, but this series is not large enough to form conclusions for this modality of treatment.

摘要

藏毛窦癌是藏毛窦疾病罕见的并发症。对于长期存在藏毛窦炎症的病例,外科医生应提高警惕。该疾病最常发生于男性。病变通常为高分化鳞状癌。在进行短暂的局部伤口护理后,初次手术时进行广泛切除是最佳治疗方法,可增加五年生存率的机会。缺损的确定性闭合延迟进行,通过旋转皮瓣或植皮完成。如果腹股沟区可触及淋巴结,即使这不一定意味着转移,也应进行活检。当存在腹股沟淋巴结转移时,预后较差。由于未进行预防性腹股沟清扫,隐匿性淋巴结转移的发生率尚不清楚。分期腹股沟清扫与任何长期生存均无关联。该系列病例数量太少,无法确定其姑息治疗潜力。放射治疗可缓解局部骨或软组织复发。局部软组织复发的再次切除在某些情况下可提供较长的无病间期。在最近的病例中应用了局部和全身化疗,但效果不佳,不过该系列病例数量不足以对这种治疗方式得出结论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba15/1345105/bfc730b823eb/annsurg00218-0125-a.jpg

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