藏毛窦癌的人口统计学概述：发病率的最新见解。

Demographic overview of pilonidal sinus carcinoma: updated insights into the incidence.

机构信息

Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Fetscherstraße 74, 01307, Dresden, Germany.

Vechtaer Institut für Forschungsförderung, VIFF e.V., Vechta, Germany.

出版信息

Int J Colorectal Dis. 2023 Feb 28;38(1):56. doi: 10.1007/s00384-023-04344-6.

DOI:10.1007/s00384-023-04344-6

PMID:36849571

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9971075/

Abstract

PURPOSE

There are only rough estimates of the worldwide incidence of pilonidal sinus carcinoma. The purpose of the study is to explore the demographic characteristics of this disease and to provide more precise information about its incidence.

METHODS

The study included questioning the surgeons and pathologists in Germany in addition to a literature research. The literature investigation included all published articles about pilonidal carcinoma in all languages. The questionnaire included 1050 pathologists and all 834 hospitals with a surgical division in Germany. The outcome measures included the total number of cases, the language of publication, gender, age, country of origin, interval until the diagnosis of carcinoma, and reported incidence based on local studies.

RESULTS

From 1900 to 2022, we found 140 cases of pilonidal sinus carcinoma in 103 articles. The investigation revealed two additional unpublished cases from Germany. The male-to-female ratio was 7.75:1. The countries with the most cases were the USA (35 cases, 25.0%), Spain (13 cases, 9.3%), and Turkey (11 cases, 7.6%). The average age was 54.0 ± 11.8 years and the interval between the diagnosis of the disease and the development of carcinoma was 20.1 ± 14.1 years. There was a parallel increase in reported cases of pilonidal sinus disease and pilonidal carcinoma over the last century. The reported incidence varied from 0.03% to 5.56%. The worldwide calculated incidence equaled 0.17%.

CONCLUSION

Due to underreporting and other causes, the incidence of carcinoma emerging on the background of pilonidal sinus disease is higher than reported.

摘要

目的

目前全球范围内关于藏毛窦癌的发病率仅有粗略估计。本研究旨在探究该疾病的人口统计学特征，并提供更精确的发病率信息。

方法

本研究通过向德国的外科医生和病理学家进行问卷调查，以及对文献进行研究，来完成调查。文献研究包括所有以各种语言发表的关于藏毛窦癌的文章。问卷涵盖了德国的 1050 名病理学家和 834 家设有外科的医院。调查结果包括病例总数、发表语言、性别、年龄、发病国、从藏毛窦发展为癌的间隔时间，以及基于当地研究的报道发病率。

结果

从 1900 年至 2022 年，我们在 103 篇文章中发现了 140 例藏毛窦癌病例。调查还发现了德国另外两例未发表的病例。男女比例为 7.75:1。病例数最多的国家为美国（35 例，25.0%）、西班牙（13 例，9.3%）和土耳其（11 例，7.6%）。平均年龄为 54.0±11.8 岁，从疾病诊断到发展为癌的间隔时间为 20.1±14.1 年。在过去的一个世纪中，藏毛窦疾病和藏毛窦癌的报道病例数呈平行增加。报道的发病率从 0.03%到 5.56%不等。全球计算的发病率为 0.17%。