[西咪替丁治疗胃溃疡]
[Cimetidine in the treatment of gastric ulcer].
作者信息
Mascarenhas e Silva R, Barbosa Sobrinho I, Fernandes R S
出版信息
Arq Gastroenterol. 1980 Apr-Jun;17(2):59-62.
PMID:7213138
Abstract
Twenty five patients with gastric ulcer were prospectively studied. They were admitted during acute phase and given cimetidine, 1000 mg/day for 6 weeks. They were maintained on cimetidine (up to 800 mg/day) for another 12 week period. The patients were studied with laboratory tests, endoscopy and biopsy during 4 steps of follow-up. A 76% healing rate was noted during the study. The incidence of side effects was low and drug tolerance and efficacy was shown to be good.
摘要
对25例胃溃疡患者进行了前瞻性研究。他们在急性期入院，给予西咪替丁，1000毫克/天，持续6周。之后再给予西咪替丁（最高800毫克/天）维持治疗12周。在随访的4个阶段对患者进行了实验室检查、内镜检查和活检。研究期间观察到愈合率为76%。副作用发生率低，且显示出良好的药物耐受性和疗效。
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