Ward R, Larivière H
Behav Genet. 1980 Jul;10(4):419-25. doi: 10.1007/BF01065604.
The degree to which mice react to light was measured by comparing open-field activities of mice produced by backcrosses involving A/J and C57BL/6J parental strains under normal white light and under dim red light. This reactivity was markedly enhanced, for pigmented mice, by rearing the animals in the dark: the reactivity of albino mice was unaffected by dark-rearing. Total activity, but not reactivity to light, was found to be influenced by the genotype of the mother, the offspring of hybrid mothers being less active than the offspring of inbred mothers. The findings are discussed in terms of the previously advanced hypothesis that retinal melanin may serve as a photochrome.
通过比较在正常白光和昏暗红光条件下，涉及A/J和C57BL/6J亲本品系回交产生的小鼠在旷场中的活动，来测量小鼠对光的反应程度。对于有色小鼠，在黑暗中饲养会显著增强这种反应性：白化小鼠的反应性不受黑暗饲养的影响。发现总活动量受母亲基因型的影响，但对光的反应性不受影响，杂交母亲的后代比近交母亲的后代活动量少。根据之前提出的视网膜黑色素可能作为一种光色素的假说对这些发现进行了讨论。
