Sartwell P E, Arthes F G, Tonascia J A
Int J Epidemiol. 1978 Sep;7(3):217-21. doi: 10.1093/ije/7.3.217.
Reproductive risk factors were estimated for 783 cases of cystic disease of the breast, 155 fibroadenoma, 94 miscellaneous breast conditions, and 284 breast cancers. Controls were matched for age, race, ever-married status, time of hospitalization and pay status. The most consistent attributes are a tendency to be still premenopausal, to have had her first pregnancy beyond the age of twenty-five years (or to have had none), and to have had fewer total pregnancies than the control. All are associated with a longer menstrual life prior to onset of the disease than the controls. Findings for cystic disease are compared with other studies. Patients with benign breast disease share some of the demonstrated risk factors for breast cancer.
对783例乳腺囊性疾病、155例纤维腺瘤、94例其他乳腺疾病及284例乳腺癌患者评估了生殖风险因素。对照组在年龄、种族、婚育状况、住院时间和付费状况方面进行了匹配。最一致的特征是倾向于仍处于绝经前、首次怀孕年龄超过25岁（或未生育）以及总怀孕次数少于对照组。所有这些都与疾病发病前比对照组更长的月经周期相关。将乳腺囊性疾病的研究结果与其他研究进行了比较。患有良性乳腺疾病的患者与一些已证实的乳腺癌风险因素有共同之处。
