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Isolation and partial structural characterization of chicken pancreatic colipase.

作者信息

Bosc-Bierne I, Rathelot J, Canioni P, Julien R, Bechis G, Gregoire J, Rochat H, Sarda L

出版信息

Biochim Biophys Acta. 1981 Feb 27;667(2):225-32. doi: 10.1016/0005-2795(81)90187-2.

Abstract

Colipase has been isolated from acidic extracts of chicken pancreatic tissue homogenized with Triton X-100. The cofactor fully activates bile salt inhibited mammalian lipases. The amino terminal sequence of the avian protein has been determined up to position 39 and compared to the homologous region of the mammalian colipases (pig, horse, man) previously studied. From this comparison, it appears that a high degree of homology exists between the proteins.

摘要

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