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肿瘤治疗评估与决策中的定性标准

Qualitative criteria in therapeutic evaluation and decision-making in oncology.

作者信息

Asselain B, Gremy F

出版信息

Bull Cancer. 1980;67(5):501-6.

PMID:7214043
Abstract

Two problems are envisaged: --the relationship between the "statistical decision" and the individual decision. Long before the existence of decision-making aids, medical knowledge has always been of a statistical nature. Ever since medicine became an organised science, the treating of a patient and not just the illness has been a constant problem. At present, it is by no means certain that we have the right to apply the strategy recommended by a well organised therapeutic trial, with our eyes shut. If for no other reason, simply because the criteria of judgment of the trial may not necessarily be the criterion best adapted to the patient concerned. --how to implicate in decision and evaluation non-quantitative criteria such as the quality of survival. Having recalled the distinction made by Wood--impairment, disability, handicap--an attempt is made to specify the state of sanometric research providing physicians with health indexes that are finer than the simple Boolean criteria of Life/Death. In conclusion, the question can be raised as to how pertinent, it is to consider death as the lowest level of health, and as to what role should be left to the patient in the choice of decision-making criteria for problems directly concerning his own fate.

摘要

有两个问题值得考虑

——“统计决策”与个体决策之间的关系。早在决策辅助工具出现之前,医学知识就一直具有统计学性质。自从医学成为一门有组织的科学以来,治疗患者而非仅仅治疗疾病一直是个持续存在的问题。目前,我们是否有权盲目应用精心组织的治疗试验所推荐的策略,这一点根本不确定。即便没有其他原因,仅仅是因为试验的判断标准不一定是最适合相关患者的标准。——如何在决策和评估中纳入非量化标准,如生存质量。在回顾了伍德所做的损伤、残疾、残障的区分之后,人们试图明确健康测量学研究的现状,该研究为医生提供比简单的生死布尔标准更精细的健康指标。总之,人们可以提出这样的问题:将死亡视为健康的最低水平有多恰当,以及在直接关乎自身命运的问题的决策标准选择上,应该给患者留什么样的角色。

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