Tamir I, Werbin B, Tenenbaum E, Pyizer R M, Levtow O, Heldenberg D
Isr J Med Sci. 1978 Sep;14(9):970-4.
Serum cholesterol was determined in the cord blood of 438 newborns and repeated on venous samples from the same infants at the ages of 6 and 18 months. Of 36 infants who were originally defined as hypercholesterolemic, 28 had normal values by the age of six months. The prevalence of hypercholesterolemia at birth was 8%. No differences were noted among the five ethnic groups examined. The results suggest that serum cholesterol level at birth is of limited value for the early detection of familial hypercholesterolemia.
对438名新生儿的脐血进行了血清胆固醇测定,并在这些婴儿6个月和18个月大时从其静脉样本中再次进行测定。最初被定义为高胆固醇血症的36名婴儿中,28名在6个月大时胆固醇值恢复正常。出生时高胆固醇血症的患病率为8%。在所检查的五个种族群体中未发现差异。结果表明,出生时的血清胆固醇水平对家族性高胆固醇血症的早期检测价值有限。