放射免疫分析显示，在假定的H-Y抗血清中不存在抗雄性特异性。
Radioimmunoassay reveals no anti-male specificity in putative H-Y antisera.
作者信息
Crichton D N, Steel C M
出版信息
Clin Exp Immunol. 1980 Dec;42(3):597-602.
Abstract
Putative anti-H-Y antisera have been examined for H-Y-specific antibody in a sensitive antiglobulin radioimmunoassay. All the sera tested were weakly bound by both male and female spleen cells. Absorption of the antisera with cells of either sex was equally effective in reducing the amount of antiglobulin bound revealing that their activity was not specific for H-Y gene products. The failure in this study to demonstrate H-Y-specific antibody is discussed.
摘要
在一项灵敏的抗球蛋白放射免疫分析中，对假定的抗H-Y抗血清进行了H-Y特异性抗体检测。所有检测的血清与雄性和雌性脾细胞均有弱结合。用任一性别的细胞吸收抗血清，在减少抗球蛋白结合量方面同样有效，这表明它们的活性并非针对H-Y基因产物。本文讨论了该研究未能证明H-Y特异性抗体的原因。
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