Wachtel S S, Koo G C, Zuckerman E E, Hammerling U, Scheid M P, Boyse E A
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1215-8. doi: 10.1073/pnas.71.4.1215.
Antisera to H-Y (male-specific) antigen were prepared by immunizing female mice with spleen cells from males of the same inbred strain. These antisera were used in mixed hemadsorption and cytotoxicity tests with cells of rats, guinea pigs, rabbits, and humans. The results showed that the H-Y components of all four species are antigenically related to H-Y of the mouse.
通过用同一近交系雄性小鼠的脾细胞免疫雌性小鼠,制备了抗H-Y(雄性特异性)抗原的抗血清。这些抗血清用于对大鼠、豚鼠、兔子和人类细胞进行混合血细胞吸附和细胞毒性试验。结果表明,所有这四个物种的H-Y成分在抗原性上与小鼠的H-Y相关。