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Allergenic potential of abietic acid, colophony and pine resin-HA. Clinical and experimental studies.

作者信息

Karlberg A T, Boman A, Wahlberg J E

出版信息

Contact Dermatitis. 1980 Dec;6(7):481-7. doi: 10.1111/j.1600-0536.1980.tb05571.x.

DOI:10.1111/j.1600-0536.1980.tb05571.x
PMID:7214893
Abstract

Resin acids are considered to be the main allergens in colophony (rosin). Tall oils also contain resin acids and may then be potential sensitizers. A resin acid concentrate (pine resin-HA) together with Chinese colophony were included in our standard series and applied on 563 patients with contact dermatitis. Fourteen showed an isolated sensitivity to colophony and two to pine resin-HA. Six patients reacted to both test compounds. Guinea pig maximization tests (Magnusson & Kligman 1969) showed that pine resin-HA (2 series) was a grade I allergen, abietic acid a grade III allergen and colophony a grade IV allergen. The risk that the resin acids in tall oils would induce contact sensitivity to workers exposed to tall oil-containing products like cutting fluids and cleansing agents is considered to be minimal.

摘要

相似文献

1
Allergenic potential of abietic acid, colophony and pine resin-HA. Clinical and experimental studies.
Contact Dermatitis. 1980 Dec;6(7):481-7. doi: 10.1111/j.1600-0536.1980.tb05571.x.
2
Contact allergy to colophony. Chemical identifications of allergens, sensitization experiments and clinical experiences.对松香的接触性过敏。变应原的化学鉴定、致敏实验及临床经验。
Acta Derm Venereol Suppl (Stockh). 1988;139:1-43.
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Contact allergy due to colophony. (IX). Sensitization studies with further products isolated after oxidative degradation of resin acids and colophony.松香引起的接触性过敏。(IX)。对树脂酸和松香氧化降解后分离出的其他产物的致敏性研究。
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[Colophony allergy. A contribution to the origin, chemistry, and uses of colophony and modified colophony products, 1].[松香过敏。对松香及改性松香产品的来源、化学性质和用途的贡献,1]
Derm Beruf Umwelt. 1982;30(4):107-15.
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Allergenic components in modified and unmodified rosin. Chemical characterization and studies of allergenic activity.改性和未改性松香中的变应原成分。化学表征及变应原活性研究。
Acta Derm Venereol Suppl (Stockh). 1994;184:1-36.
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Contact allergy to colophony. Clinical and experimental studies with emphasis on clinical relevance.对松香的接触性过敏。侧重于临床相关性的临床与实验研究。
Acta Derm Venereol Suppl (Stockh). 1998;201:1-42.
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Contact allergy due to colophony (III). Sensitizing potency of resin acids and some related products.
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Clinical experience and patch testing using colophony (rosin) from different sources.临床经验以及使用不同来源的松香进行斑贴试验。
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Colophony allergy: a review.
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Contact allergy to acid and neutral fractions of rosins. Sensitization experiments in guinea pigs and patch testing in patients.对松香酸和中性组分的接触性过敏。豚鼠致敏实验及患者斑贴试验。
Derm Beruf Umwelt. 1986 Mar-Apr;34(2):31-6.

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Immune responses to colophony, an agent causing occupational asthma.对导致职业性哮喘的一种物质——松香的免疫反应。
Thorax. 1992 Dec;47(12):1050-5. doi: 10.1136/thx.47.12.1050.