Lusser G M, Müller J
Helv Chir Acta. 1978 Dec;45(4-5):595-602.
In treating patients who present with an extensive non-union due to infected intramedullary nail, bone healing can be achieved within a few weeks through a policy of active management. Following excision of the infected tissue and thorough irrigation, the fracture site is stabilized by a plate fixation and a packet with cancellous bone. The wound overlying the bone is left open to granulate. No complications were observed during the course of healing in 7 cases (5 tibia, 2 femur) managed this way. The method is based on classical principles of orthopedics and the treatment of infection. Such has been its impressive success, that it would seem to warrant not only close attention but also strong recommendation.
在治疗因髓内钉感染导致广泛骨不连的患者时，通过积极的治疗策略，数周内即可实现骨愈合。切除感染组织并彻底冲洗后，骨折部位用钢板固定，并植入松质骨包块。覆盖骨骼的伤口敞开以形成肉芽组织。采用这种方法治疗的7例患者（5例胫骨，2例股骨）在愈合过程中未观察到并发症。该方法基于骨科和感染治疗的经典原则。其取得的显著成功不仅值得密切关注，也值得大力推荐。
