肝外胆管闭锁患儿胆管残余部位的免疫球蛋白沉积：128例婴儿的免疫过氧化物酶染色研究
Immunoglobulin deposits in the biliary remnants of extrahepatic biliary atresia: a study by immunoperoxidase staining in 128 infants.
作者信息
Hadchouel M, Hugon R N, Odievre M
出版信息
Histopathology. 1981 Mar;5(2):217-21. doi: 10.1111/j.1365-2559.1981.tb01779.x.
Abstract
Bile duct remnants taken from 128 infants during surgery for extrahepatic biliary atresia were paraffin embedded prior to immunoperoxidase staining. Immunoglobulin deposits were found in 44 remnants. They were made up of IgM alone in 25 cases and of IgM and IgG in 19. Deposits were observed along the basement membranes of glandular structures. These findings suggest that extrahepatic biliary atresia might be an acquired and evolving disease.
摘要
在对128例肝外胆管闭锁婴儿进行手术时获取的胆管残余组织，在进行免疫过氧化物酶染色前进行了石蜡包埋。在44个残余组织中发现了免疫球蛋白沉积。其中25例仅由IgM组成，19例由IgM和IgG组成。在腺结构的基底膜上观察到沉积物。这些发现表明肝外胆管闭锁可能是一种后天获得性且不断发展的疾病。
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