Gautier M, Eliot N
Arch Pathol Lab Med. 1981 Aug;105(8):397-402.
Histologic examination was performed on 98 biliary remnants. Classification into three types was made according to the presence of epithelial structure; biliary and glandular formations had to be separated. Atretic lesions were predominantly observed at the pars inferior of the remnants. These histological findings agree with the theory of a dynamic ascending process that leads to progressive, complete destruction of the biliary and glandular structure, although main ducts may remain preserved by the vicinity of the porta hepatis. Classic clinical data suggest that the damage is initiated in utero. The lesions certainly progress after birth; in some cases the fibrotic process of the remnant may have already reached completion at birth, whereas in some others it may become clinically evident after birth.
对98个胆管残留组织进行了组织学检查。根据上皮结构的存在将其分为三种类型；胆管和腺体结构必须分开。闭锁性病变主要见于残留组织的下部。这些组织学发现与动态上升过程的理论相符，该过程导致胆管和腺体结构逐渐完全破坏，尽管主要胆管可能因肝门附近而得以保留。经典临床资料表明，损伤始于子宫内。病变在出生后肯定会进展；在某些情况下，残留组织的纤维化过程在出生时可能已经完成，而在另一些情况下，可能在出生后才在临床上显现出来。
