Lahmeyer H W, Steingold R G
Int J Addict. 1980 Nov;15(8):1219-32. doi: 10.3109/10826088009040092.
The change in illicit drug use from 1975 to 1978 was studied in Chicago veterans. Barbiturates and amphetamine use has decreased significantly. Nearly a sevenfold increase in pentazocine use has occurred. All but one of the pentazocine users added tripelennamine to the intravenous or subcutaneous injections. Sixty-four instances of medical or psychiatric complications including seizures, abscesses, depression, and psychosis occurred in the 69 pentazocine and tripelennamine users. A possible pharmacologic explanation of the seizures and psychiatric complications is advanced. Most users of pentazocine and tripelennamine started the use in an attempt to withdraw from heroin or because of the poor quality of heroin available.
对芝加哥退伍军人1975年至1978年期间非法药物使用情况的变化进行了研究。巴比妥类药物和安非他明的使用显著减少。喷他佐辛的使用增加了近七倍。除一名喷他佐辛使用者外，其他使用者均在静脉注射或皮下注射时添加了曲吡那敏。69名喷他佐辛和曲吡那敏使用者出现了64例包括癫痫发作、脓肿、抑郁和精神病在内的医学或精神并发症。对癫痫发作和精神并发症提出了一种可能的药理学解释。大多数喷他佐辛和曲吡那敏使用者开始使用这些药物是为了戒除海洛因或因可获得的海洛因质量差。
