Kendall M D, Johnson H R, Singh J
J Anat. 1980 Oct;131(Pt 3):483-97.
The wet, lipid and lean dry weights of 574 thymus glands from Coroner's necropsies were examined for age-related changes. Despite enormous variation in wet and lipid weights at all ages there was a gradual decrease in wet weight with age and a significant increase in lipid weight until 40--50 years of age, with little change thereafter. There was a small decrease in lean dry weight with age, but it is not known if this reflects a change in cellularity. Multiple regression analysis showed that lower wet and lipid thymic weights were associated with long-term stressful conditions, and higher weights with deaths from asphyxia (largely in younger persons) and five groups of cardiovascular conditions. The percentage of lipid in these groups was not increased.
对574份来自死因裁判尸检的胸腺的湿重、脂质重和去脂干重进行了检查，以研究与年龄相关的变化。尽管各年龄段的湿重和脂质重差异极大，但湿重随年龄逐渐下降，脂质重在40至50岁之前显著增加，此后变化不大。去脂干重随年龄略有下降，但尚不清楚这是否反映了细胞数量的变化。多元回归分析表明，胸腺湿重和脂质重较低与长期应激状况相关，而较高的重量与窒息死亡（主要是年轻人）以及五组心血管疾病的死亡相关。这些组中的脂质百分比并未增加。
