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噬菌体P1的dnaB类似物(ban蛋白)对dnaC等位基因的抑制作用。

Suppression of dnaC alleles by the dnaB analog (ban protein) of bacteriophage P1.

作者信息

Sclafani R A, Wechsler J A

出版信息

J Bacteriol. 1981 Apr;146(1):321-4. doi: 10.1128/jb.146.1.321-324.1981.

DOI:10.1128/jb.146.1.321-324.1981
PMID:7217002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC217085/
Abstract

The dnaB analog protein produced by the ban gene of bacteriophage P1 was shown to suppress several Escherichia coli dnaC alleles. Suppression of dnaC7 temperature sensitivity in P1 lysogens of a dnaC7 mutant was complete at all temperatures. For the dnaC2 and dnaC28 alleles, suppression was observed only at intermediate temperatures. Though these intermediate temperatures were sufficient to completely restrict the mutants, at higher temperatures the suppression was not observed. No suppression of the dnaC1 allele was detected. These results have implications concerning the requirement for the dnaB-dnaC complex at the various stages of deoxyribonucleic acid replication.

摘要

噬菌体P1的ban基因产生的dnaB类似蛋白可抑制几种大肠杆菌dnaC等位基因。在dnaC7突变体的P1溶原菌中,dnaC7温度敏感性在所有温度下均被完全抑制。对于dnaC2和dnaC28等位基因,仅在中间温度下观察到抑制作用。尽管这些中间温度足以完全限制突变体,但在较高温度下未观察到抑制作用。未检测到对dnaC1等位基因的抑制作用。这些结果对脱氧核糖核酸复制各个阶段对dnaB-dnaC复合物的需求具有启示意义。

相似文献

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Suppression of dnaC alleles by the dnaB analog (ban protein) of bacteriophage P1.噬菌体P1的dnaB类似物(ban蛋白)对dnaC等位基因的抑制作用。
J Bacteriol. 1981 Apr;146(1):321-4. doi: 10.1128/jb.146.1.321-324.1981.
2
The isolation and characterization of escherichia coli dnaB::Tn10 insertion mutations.大肠杆菌dnaB::Tn10插入突变的分离与鉴定
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A dnaB analog function specified by bacteriophage P7 and its comparison to the similar function specified by bacteriophage P1.噬菌体P7所指定的dnaB类似功能及其与噬菌体P1所指定的类似功能的比较。
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引用本文的文献

1
Bacteriophage P1 Ban protein is a hexameric DNA helicase that interacts with and substitutes for Escherichia coli DnaB.噬菌体P1 Ban蛋白是一种六聚体DNA解旋酶,它与大肠杆菌DnaB相互作用并替代后者。
Nucleic Acids Res. 2003 Jul 15;31(14):3918-28. doi: 10.1093/nar/gkg463.
2
The dnaC protein of Escherichia coli. Purification, physical properties and interaction with dnaB protein.大肠杆菌的dnaC蛋白。纯化、物理性质及与dnaB蛋白的相互作用。
Nucleic Acids Res. 1983 Feb 25;11(4):987-97. doi: 10.1093/nar/11.4.987.
3
Continuous synthesis of the dnaA gene product of Escherichia coli in the cell cycle.大肠杆菌细胞周期中dnaA基因产物的持续合成。
Mol Gen Genet. 1982;186(1):87-94. doi: 10.1007/BF00422917.
4
Genetic analysis of DNA replication in bacteria: dnaB mutations that suppress dnaC mutations and dnaQ mutations that suppress dnaE mutations in Salmonella typhimurium.细菌中DNA复制的遗传分析:鼠伤寒沙门氏菌中抑制dnaC突变的dnaB突变以及抑制dnaE突变的dnaQ突变
Genetics. 1984 Sep;108(1):25-38. doi: 10.1093/genetics/108.1.25.

本文引用的文献

1
Deoxyribonucleic acid initiation mutation dnaB252 is suppressed by elevated dnaC+ gene dosage.脱氧核糖核酸起始突变dnaB252可被升高的dnaC +基因剂量所抑制。
J Bacteriol. 1981 Apr;146(1):418-21. doi: 10.1128/jb.146.1.418-421.1981.
2
Synthesis of P1 ban protein in minicells infected by P1 mutants.P1突变体感染的微小细胞中P1禁令蛋白的合成。
Mol Gen Genet. 1980 Jan;177(2):193-7. doi: 10.1007/BF00267429.
3
Escherichia coli mutants temperature-sensitive for DNA synthesis.对DNA合成温度敏感的大肠杆菌突变体。
Mol Gen Genet. 1971;113(3):273-84. doi: 10.1007/BF00339547.
4
Escherichia coli mutants with temperature-sensitive synthesis of DNA.具有温度敏感型DNA合成能力的大肠杆菌突变体。
Mol Gen Genet. 1970;109(2):107-22. doi: 10.1007/BF00269647.
5
Genetic control of DNA initiation in Escherichia coli.大肠杆菌中DNA起始的遗传控制。
J Mol Biol. 1973 Feb 25;74(2):205-21. doi: 10.1016/0022-2836(73)90107-1.
6
A dnaB analog specified by bacteriophage P1.由噬菌体P1指定的一种dnaB类似物。
J Mol Biol. 1975 May 25;94(3):341-66. doi: 10.1016/0022-2836(75)90207-7.
7
Genetic and phenotypic characterization of dnaC mutations.dnaC 突变的遗传和表型特征分析
J Bacteriol. 1975 Feb;121(2):594-9. doi: 10.1128/jb.121.2.594-599.1975.
8
A dnaB analog ban, specified by bacteriophage P1: genetic and physiological evidence for functional analogy and interactions between the two products.噬菌体P1指定的dnaB类似物禁令:两种产物之间功能类似性及相互作用的遗传学和生理学证据
Mol Gen Genet. 1979 Jul 13;174(2):173-88. doi: 10.1007/BF00268354.
9
Association of the prophage P1ban protein with the dnaB protein of Escherichia coli. Overproduction of ban protein by a P1bac crr mutant.
Eur J Biochem. 1979 Mar;94(2):427-35. doi: 10.1111/j.1432-1033.1979.tb12910.x.
10
Association of the prophage P1ban protein with the dnaB protein of Escherichia coli.
J Biol Chem. 1978 Jul 10;253(13):4746-53.