噬菌体P1的dnaB类似物（ban蛋白）对dnaC等位基因的抑制作用。
Suppression of dnaC alleles by the dnaB analog (ban protein) of bacteriophage P1.
作者信息
Sclafani R A, Wechsler J A
出版信息
J Bacteriol. 1981 Apr;146(1):321-4. doi: 10.1128/jb.146.1.321-324.1981.
Abstract
The dnaB analog protein produced by the ban gene of bacteriophage P1 was shown to suppress several Escherichia coli dnaC alleles. Suppression of dnaC7 temperature sensitivity in P1 lysogens of a dnaC7 mutant was complete at all temperatures. For the dnaC2 and dnaC28 alleles, suppression was observed only at intermediate temperatures. Though these intermediate temperatures were sufficient to completely restrict the mutants, at higher temperatures the suppression was not observed. No suppression of the dnaC1 allele was detected. These results have implications concerning the requirement for the dnaB-dnaC complex at the various stages of deoxyribonucleic acid replication.
摘要
噬菌体P1的ban基因产生的dnaB类似蛋白可抑制几种大肠杆菌dnaC等位基因。在dnaC7突变体的P1溶原菌中，dnaC7温度敏感性在所有温度下均被完全抑制。对于dnaC2和dnaC28等位基因，仅在中间温度下观察到抑制作用。尽管这些中间温度足以完全限制突变体，但在较高温度下未观察到抑制作用。未检测到对dnaC1等位基因的抑制作用。这些结果对脱氧核糖核酸复制各个阶段对dnaB-dnaC复合物的需求具有启示意义。
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