Callen J P
J Am Acad Dermatol. 1981 Feb;4(2):149-51. doi: 10.1016/s0190-9622(81)70017-3.
Intralesional corticosteroids are commonly used in clinical dermatology. They are an adjunct to topicals and a possible substitution for systemic corticosteroids. Intralesional corticosteroids can be injected via a syringe and needle or with a Dermo-Jet. Although multiple preparations are available, the triamcinolones have more acceptable physical characteristics. Systemic absorption and consequent adverse effects are rarely a problem because of low dosage administered. Local adverse effects (the most prominent of which is atrophy) depend on the strength of the preparation, the quantity used, the area of the body, and the skin condition being treated.
皮损内注射皮质类固醇激素在临床皮肤科中常用。它们是外用药物的辅助手段,也是全身用皮质类固醇激素的一种可能替代物。皮损内注射皮质类固醇激素可通过注射器和针头或使用皮肤喷射器进行注射。尽管有多种制剂可供使用,但曲安奈德类药物具有更易接受的物理特性。由于给药剂量低,全身吸收及随之而来的不良反应很少成为问题。局部不良反应(其中最突出的是萎缩)取决于制剂的强度、使用量、身体部位以及所治疗的皮肤状况。