Sakhiya Jagdish, Sakhiya Dhruv, Kaklotar Jitesh, Hirapara Bansi, Purohit Madhav, Bhalala Krishna, Daruwala Feral, Dudhatra Nimish
Sakhiya Skin Clinic, 2nd Floor, Ayush Doctor House, Station-Lal Darwaja Road, Surat, Gujarat, India.
B.J. Medical College, New Civil Hospital Asarwa, Ahmedabad, Gujarat, India.
J Cutan Aesthet Surg. 2021 Jul-Sep;14(3):285-295. doi: 10.4103/JCAS.JCAS_109_20.
Since introduced in 1961, intralesional (IL) agent has become an essential part of the dermatological practice. The term IL referred to the direct delivery of agent percutaneously into skin lesions. This therapeutic approach is relatively safe, easy to perform and applicable for a broad range of dermatological conditions. On the other hand, immediate side effects, including pain during administration, bleeding, high risk of infection and allergic reaction, and subsequent side effects involving skin changes such as atrophy, telangiectasia, pigmentary changes, and striae are usually associated with this modality. This review paper highlights the pros and cons of IL agents in modern dermatology practice.
自1961年引入以来，皮损内（IL）注射药物已成为皮肤科临床实践的重要组成部分。术语“IL”指的是将药物经皮直接注射到皮肤病变部位。这种治疗方法相对安全、易于实施，适用于多种皮肤病。另一方面，即时副作用，包括给药时的疼痛、出血、感染和过敏反应的高风险，以及随后涉及皮肤变化的副作用，如萎缩、毛细血管扩张、色素沉着变化和萎缩纹，通常与这种治疗方式相关。这篇综述文章强调了IL药物在现代皮肤科实践中的利弊。
