[搭载生物卫星“宇宙-936”飞行后大鼠前臂骨中的磷酸酶活性]
[Phosphatase activity in the forearm bones of rats after a flight aboard the biosatellite "Cosmos-936"].
作者信息
Popova I A, Tigranian R A
出版信息
Kosm Biol Aviakosm Med. 1981 Jan-Feb;15(1):82-4.
Activities of alkaline and acid phosphatases in ulnar and radial bones of rats flown for 18.5 days aboard Cosmos-936 and kept in a ground-based mock-up were investigated. In both bones activity of acid phosphatase increased significantly and that of alkaline phosphatase decreased 6--10 hours postflight; in the synchronous experiment the only change was a decrease in the activity of alkaline phosphatase in the radius. An exposure of rats to artificial gravity did not normalize changes in phosphatase activities observed postflight. At R + 25 phosphatase activity in bones of flight rats returned to normal and even tended to exceed the control level in synchronous animals.
对搭乘“宇宙-936号”飞船飞行18.5天并饲养在地面模拟装置中的大鼠尺骨和桡骨的碱性磷酸酶及酸性磷酸酶活性进行了研究。飞行后6 - 10小时，两根骨头的酸性磷酸酶活性均显著增加，碱性磷酸酶活性下降；在同步实验中，唯一的变化是桡骨碱性磷酸酶活性下降。让大鼠暴露于人工重力环境并不能使飞行后观察到的磷酸酶活性变化恢复正常。在飞行后第25天，飞行大鼠骨骼中的磷酸酶活性恢复正常，甚至有超过同步饲养动物对照水平的趋势。
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